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David Brand was born in Stanthorpe, Queensland. After graduating in medicine from the University of Queensland in 1955, he began training in internal medicine at the Royal Brisbane Hospital where he was Resident Medical Officer and registrar from 1956 to 1958, registrar at Princess Alexandra Hospital in 1959, and teaching registrar in medicine at the University of Queensland from 1960 to 1961. He subsequently became a consultant physician to the Royal Brisbane Hospital from 1963 to 1980, and was engaged in private practice from his rooms in Wickham Terrace.
David served in the Royal Australian Air Force (RAAF) from 1940 to 1945, and was later Flight Lieutenant RAAF Reserve. In 1981, he made a major career change and for some years he accepted appointments in internal medicine in a number of cities in the Middle East including Al Khobal, Dhahran and Riyadh.
After completing his Middle East assignments he returned to Australia, and at the time of his death he was a resident of Huntingdale in Western Australia.