I graduated from the University of Hong Kong in 1974, with the C.P.Fong gold medal in Medicine and was awarded the Chan Kai Ming Prize (given to the student who tops the marks in the final MBBS examination). I emigrated to Australia after finishing my internship in Hong Kong and completed my postgraduate training in general medicine and nephrology in Adelaide and Sydney, obtaining my FRACP in 1982. I then underwent basic research into the immunopathogenesis of glomerulonephritis and was awarded my PhD from the University of Sydney in 1987.

I returned to Hong Kong in 1986, and joined the University of Hong Kong, first as a lecturer, and rose through the ranks to Reader in 1992. I was appointed consultant physician at the Queen Mary and Tung Wah Hospitals from 1986 to 1990, and chief of Division of Nephrology from 1990 to 1996. In 1996, I went into private practice and was appointed Honorary Associate, and later Honorary Clinical Professor at the University of Hong Kong until my retirement in 2018.

Throughout my career, I was actively involved in clinical research in nephrology and published more than 128 papers in peer reviewed international and regional journals, and 2 chapters in nephrology textbooks. Apart from my Australian Fellowship, I obtained Fellowship of the Hong Kong College of Physicians in 1987, and was elected Fellow of the Hong Kong Academy of Medicine in 1993, and the Royal Colleges of Physicians of London and Edinburgh in 1995 and 1996, respectively. Apart from clinical research, I was also active in promoting academic and clinical exchanges with fellow nephrologists at the local, regional and international levels.

I was appointed to the editorial boards of the Hong Kong Journal of Nephrology, Journal of the Hong Kong Society of Nephrology, Nephrology and Peritoneal Dialysis International. I was elected Chairman of the Hong Kong Society of Nephrology and was the founding Chairman of the Hong Kong Society of Transplantation. For more than ten years, I was a Council member, Treasurer and then Secretary of the Asian Pacific Society of Nephrology, and Council member and Treasurer of the Asian Society of Transplantation. I was President and Member of the Scientific Committee of the 6th Asian Pacific Congress of Nephrology in Hong Kong in 1995.

Apart from my academic, clinical and professional career, I was also actively involved in patient related activities being a past member of the Central Renal Committee and Transplant Organ Board of the Hong Kong SAR Government, the Organ Donation Register Fund of the Hong Kong Medical Association and the Hong Kong Kidney Foundation, Honorary Chairman of the Renal Companion Association and Honorary Advisor/member of the Lions Kidney Education Centre and Research Foundation, the Alliance for Patients' Self Help Organisation and the Hong Kong Lupus Association. In 2018, I retired and passed my private practice to my partner of more than 10 years.