Paracetamol use in pregnancy – statement from the PCHD President

The RACP and its Paediatrics & Child Health Division (PCHD) are concerned about a recent announcement from the United States suggesting a causal link between acetaminophen use in pregnancy (known as Tylenol in the US and paracetamol or Panadol equivalent in Australia) and autism spectrum disorder in children.

These claims are not supported by scientific research or evidence, clinical experts, medical and healthcare professionals, researchers or scientists.

Australia’s Chief Medical Officer and the Australian Therapeutic Goods Administration,
released a statement rejecting the US claims regarding the use of paracetamol in
pregnancy.

In this statement it is noted that 'robust scientific evidence shows no causal link between the use of paracetamol in pregnancy and autism or ADHD, with several large and reliable studies directly contradicting these claims'.

While some recently reported studies have reported an association between acetaminophen or paracetamol use and autism, others have not. It is important to understand that association does not imply causation.

Paracetamol is a Pregnancy Category A medication and remains the recommended treatment option for fever or pain in pregnant women, when used as directed. Untreated fever or pain can pose risks to an unborn baby and managing these symptoms with appropriate treatment is important.

Pregnant women should speak to qualified healthcare professionals if they have questions about any medication during pregnancy.

Women who have concerns and are pregnant, or considering pregnancy, are also advised to consult a qualified healthcare professional to discuss their concerns.

Autism is a complex neurodevelopmental condition with no known single cause. Our current understanding of autism is that it is a neurodevelopmental condition that is influenced by both genetic and environmental causes.

We encourage public conversation about autism to be respectful and considered,
grounded in robust scientific research and evidence, and consider the needs and interests of autistic people.

Dr Niroshini Kennedy
PCHD President