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Genomics has allowed increasingly rapid development highly-targeted cancer drugs and unprecedented improvements in outcomes for patients with more common cancers. Now, patients with rare cancers also have some hope in the form of tissue-agnostic therapies.

[Case Report] 35yo male with proximal weakness and skin changes

A previously-well patient presents with progressive weakness in the proximal lower limbs and trunk and a generalized change to the skin. There are many differential diagnoses to be considered.

[Case Report] 47yo with rapidly progressive respiratory failure requiring ECMO

A patient admitted for worsening breathlessness and a productive cough experiences rapidly progressive respiratory failure. His workup involves a battery of investigations and interventions from the respiratory medicine textbook.

[Journal Club] Thrombolysis up to 24hr after ischaemic stroke

Thrombolysis can buy valuable time for patients who experience acute ischaemic stroke but two thirds of them present outside the recommended window. A recently published study shows that tenecteplase improves outcomes in selected patients even if administered up to 24 hours from onset of a large vessel occlusion.

[Case Report] 48yo with diarrhoea and lymphadenopathy

A man presenting with a 3-month history of diarrhoea has a complex range of accompanying symptoms and investigative results.

[Guest Lecture] Fighting hepatitis C in prisons and the community

NSW is on track to meet the state and federal targets for the elimination of hepatitis C. But an adaptable approach to surveillance and intervention is required, particularly in correctional settings which have high rates of transmission.

Ep115: One day as a nuclear medicine registrar

In this “reality audio” podcast we get a taste of the daily tasks and responsibilities of an advanced trainee in nuclear medicine. There is a broad mix of cases and professional collaborations.

[IMJ On-Air] Understanding readmissions better

Today’s IMJ paper describes the validation and of a prognostic algorithm for predicting the likelihood of 30 day readmissions, and how this can be implemented to improve practice.

[Case Report] 58yo with acute myeloid leukaemia and diplopia

This podcast follows the case of a patient with acute myeloid leukaemia who developed neurological symptoms after initiating chaemotherapy.

Ep112: The resilient workplace

This podcast challenges some established notions about workplace mental distress and how to treat it. It also shifts the conception of health as something not just dependent on the presence or absence of disease.

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